With Undimensioned and Unseen, we might have seen the first real target for Mind Wipe. And man is it a big one. Spoilers ahead:

Taking down a Brood of Yog-Sothoth is no easy task. First, you need to find the Esoteric Formula before you can even attack it. Then, you are faced with making a combat check against 6 to damage it - made easier by clues you can put on it, but 6 is nevertheless the highest combat we've seen on an enemy thus far. Even if you succeed, you only deal one damage to it, whereas it has 2-5 health depending on how many investigators you are playing with.

Or, you can skip all that and play Mind Wipe. Better yet, since you are probably playing Agnes Baker anyway and have Forbidden Knowledge, immediately follow up with taking 1 horror using Forbidden Knowledge and kill a house sized invisible monstrosity without breaking a sweat.

Oh, but you don't get its Victory I. But I think that's a fair price to pay for the amount of effort you save.

This Card can be played after Double or Nothing, as it raises the difficulty (if the resulting difficulty is 2 higher than your base value). This card refers to the modified difficulty of a test, not the base value.

With +3 to any test, this is very cost effective solution to resolve Tests, with Double or Nothing, even if another Player uses her Double or Nothing for you.

• Can you use this ability when you draw a treachery weakness card (like Abandoned and Alone)?
• Is the drawn card considered "in hand" when you use this ability? If not, it would allow you to discard agnes's weakness without effect.

After this card is resolved, it's placed in the now empty discard pile. So if this is the last card in your deck, it removes the remaining discard pile from the game when you draw it and when you're required to draw a card again, it's the only card in your new deck. So you take 2 direct horror each turn, because it's the only card to draw each time.

I'm not sure about about Liquid Courage for many of the investigators in the core set/Dunwich legacy. To be honest, the investigators who struggle with Sanity - e.g. Roland Banks, or "Skids" O'Toole - also tend to have low willpower, so this isn't so useful for them.

Zoey Samaras can make pretty good use of it, particularly if she has something to give Willpower a boost, and her sanity is low enough to need a little help.

However, I've found it fantastic for... Agnes Baker. Yes, she can't actually take this card herself - but another investigator can, and then use liquid courage to heal Agnes' horror. This lets her use her ability to inflict damage when she takes horror even more often, which is awesome, and her 5 makes it unlikely that she'll fail the test to heal the second horror very often.

So if you're hunting Great Old Ones with Agnes at your side, embrace sociable investigating! Come 'ere Agnes, and have wee dram for yer nerves...