Delay the Inevitable is generally not very good in ordinary . The most reliable way to trigger the card is through an enemy attack, which Dodge does a better job. Sure it can cancel damage/horror from encounter cards, but there is no guarantee that you will draw those treacheries. The 2 resources upfront + 2 resources upkeep cost could also be painful. It has some use to protect a near-defeat teammate (literally delaying his/her inevitable death :D), but that is not a scenario that comes off too often in my experience.

That said, the card is oddly useful in the 3 Circle Undone investigators that can use it, in interestingly different ways.

Carolyn Fern has better econ to use the card, and has less chance to need to fight an enemy so Dodge is not as useful. Also, if you use her replacement cards, Delay the Inevitable can help to cancel the direct horror from To Fight the Black Wind, thus prevent the doom to be placed on the agenda.

Joe Diamond like the card in his Hunch deck. It is a 2-cost fast Insight, which is just perfect for the Hunch deck. It becomes essentially free (outside of opportunity cost), that you can play it with ease, and not be too afraid if it whiffs.

Diana Stanley may want the card as an additional cancel to fuel her ability. Part of the card's cost is mitigated through her ability. Note that Diana's ability only activates when the card actually cancels something, so the partial cost reimbursement is delayed. It usually is a downside, but it may be useful to trigger Diana's ability out of phase. Certainly worse than Deny Existence though, but Diana may nonetheless want both.

Fun fact: Delay the Inevitable (along with Deny Existence mentioned above) can cancel Beyond the Veil. Maybe not so funny to Yog-Sothoth though.

This card is in a lot perspective similar to Scene of the Crime, that it is hard to not make a comparison:

Similarities:

• Cost 2, which is non-trivial in the resource-hungry class.
• Gather 2 clues in 1 action while ignoring shroud-value and investigate-based effects. Great value! Combat fucused often lack ways to gather even a single clue, let alone multiple clues. Amazing.
• Requires an enemy at your location. This is kind of annoying, since as a it is your job to kill the enemy at first sight. Spending an action on clue gathering may leave you insufficient action to finish off the enemy, or otherwise more vulnerable to auto-failing attacks.
• Same set of icons ( + ), which is mildly useful.

Pros:

• Does not need to be the first action. It adds some flexibility that you can move into the Humanoid's location before you use this card.
• 1 of the 2 clues comes from any other location you choose, which may be useful if the enemy does not conveniently spawn on the hard-to-investigate locations.

Cons:

• Literally unplayable without an enemy, while Scene of the Crime just become worse but still decent.
• The enemy needs to have the Humanoid trait, which may not even exist for certain scenarios.
• This card requires a test of usually 4, which even the best has a realistic chance to fail.

Sadly the comparison with Scene of the Crime is unfavorable. The flexibility that Interrogate offers, IMHO, does not outweigh Scene of the Crime's reliability. That said, Scene of the Crime is the single best clue-gathering card. As a card comparable to it, Interrogate is still quite a good card.

Reasons to run Interrogate in addition to Scene of the Crime:

• Your party lack clue-gathering power.
• You know the scenario will contain a lot of Humanoids, like those feature the Dark Cult encounter set. Better if you have access to Adaptable (Leo and Skids).
• You are Joe Diamond and you want more clue-gathering stuffs in your Hunch deck, and/or need a way to pick up the lost clue due to Unsolved Case.
• You have the econ to pay both cards.

Reasons to run Interrogate instead of Scene of the Crime:

• You are playing Solo, that double clue locations are rare. 1 clue each from different locations often cleans both up, which is amazingly good for one action. Keep in mind that enemies are also rarer in Solo, so it could be a bit more situational.

Pros:

1. Strong signature cards (especially Dark Insight)
2. Decent intellect and strength
3. +1 resource/ +1 card activated effect is strong incentive to play ignore/cancel effects, since it often makes them free cantrips. This also makes her deck cycle faster.
4. Access to cards, which increases her potential for combat
5. Potential for 6 base willpower in late game
6. She starts with 6 cards (with Dark Insight as one of them), and if you mulligan you can get up to 6 new cards!
7. I think her signature weakness is not as devastating as many others. You can choose which cards to ditch and which to keep for 1 horror. This actually helps clear space for new additions. But it also favors not relying too heavily on her willpower (see below).

Cons:

1. Very low starting willpower. This creates a conundrum because cards like Shrivelling will be very difficult to use for part of the game, and hard to justify with access to cards like Machete. Upgraded spells that boost willpower should be easier to use. If you do rely heavily on willpower, it incentivizes playing your cancel/ignore effects earlier, and even potentially wasting them instead of saving them for harsher threats.
2. Why choose Diana Stanley to wield Machete when you can use other guardians with 4 or 5 strength? I think you have to make good use of her cards and 3 intellect to justify this.

This card is best with Diana, for whom (as long as you have an open spot beneath her) it replaces itself and gives +1 resource (same net bonus as Emergency Cache). It might be usable in some other decks, especially if you are trying to increase your spell count (for Arcane Initiate, etc). Awesome artwork, too!

For reference, as of The Circle Undone, here is a list of negative effects that Eldritch Inspiration can be used to mitigate:

Alchemical Transmutation - Take 1 damage.
Astral Travel - Discard an item or ally asset from play, take 1 damage if you cannot.
Blinding Light - Lose 1 action.
Blinding Light (2) - Lose 1 action and take 1 horror.
Mists of R'lyeh & Mists of R'lyeh (2) - Choose and discard a card.
Recharge (2) - Discard the chosen asset. (Note: You still don't get the 3 charges in this case.)
Rite of Seeking & Rite of Seeking (2) & Rite of Seeking (4) - Lose all remaining actions and end your turn.
Seal of the Seventh Sign (5) - Remove 1 charge from Seal of the Seventh Sign.
Shrivelling & Shrivelling (3) - Take 1 horror.
Shrivelling (5) - Take 2 horror.
Storm of Spirits - Deal 1 damage to each investigator at your location.
The Chthonian Stone - Return The Cthonian Stone to your hand.

Here is a list of positive effects that can be doubled using Eldritch Inspiration:

Eldritch Inspiration - Can actually be used on a second copy of itself, but it won't quadruple the effect it will just triple it.
Hypnotic Gaze - Deal an attacking enemy's damage to itself.
Jewel of Aureolus (2) - Draw a card or gain 2 resources.
Recall the Future (2) - +2 skill value for this test (named , , , or token only).
Ritual Candles - +1 skill value for this test.
Song of the Dead (2) - +2 damage ( only).

Note that and on cards will count as triggers for this card, as per the Rules Reference. Father Mateo doesn't actually get an additional benefit from repeating his conversion of to , and Jim Culver's to 0 conversion is static and not a trigger.